In 2022, the population of Epes was 263, a 1.50% decrease year-by-year from 2021. Previously, in 2021, Epes's population was 267, a decline of 0.74% compared to a population of 269 in 2020.
The median age in Epes, AL is 36.3, as per 2021 ACS 5-Year Estimates. Of the total population, 13.55% were under the age of 15, 33.55% aged 15 to 29, 45.81% aged 30 to 64, 7.10% aged 65 to 84, and 0.00% were 85 years of age and older.