In 2022, the population of De Witt was 84, a 0.00% decrease year-by-year from 2021. Previously, in 2021, De Witt's population was 84, a decline of 1.18% compared to a population of 85 in 2020.
The median age in De Witt, MO is 66.3, as per 2021 ACS 5-Year Estimates. Of the total population, 0.00% were under the age of 15, 4.35% aged 15 to 29, 30.43% aged 30 to 64, 52.17% aged 65 to 84, and 13.04% were 85 years of age and older.